A REAL-WORLD DISPROPORTIONALITY ANALYSIS OF CYCLOSPORINE FROM THE FDA ADVERSE EVENT REPORTING SYSTEM (FAERS) DATABASE

A real-world disproportionality analysis of cyclosporine from the FDA Adverse Event Reporting System (FAERS) database

Cyclosporine is an immunosuppressant used to prevent organ rejection in kidney, liver, and heart allogeneic transplants.This study aimed to assess the safety of cyclosporine through the analysis of adverse events (AEs) related to cyclosporine in the US Food and Drug Administration Adverse Event Reporting System (FAERS).To detect AEs associated with

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Establishment and validation of a cholesterol metabolism-related prognostic signature for hepatocellular carcinoma

Hepatocellular carcinoma (HCC) represents the most important type of liver cancer, the 5-year survival rate for advanced HCC is 2%.The heterogeneity Mystery Mini of HCC makes previous models fail to achieve satisfactory results.The role of Cholesterol-based metabolic reprogramming in cancer has attracted more and more attention.In this study, we sc

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Short-Term Statistical Forecasts of COVID-19 Infections in India

COVID-19 cases in India have been steadily increasing since January 30, 2020 and have led to a government-imposed lockdown across the country to curtail community transmission with significant impacts on societal systems.Forecasts using mathematical-epidemiological models have played and continue to play an important role in assessing the probabili

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Epigenetic DNA Methylation Linked to Social Dominance.

Social status hierarchies are ubiquitous in vertebrate social systems, including humans.It is well known that social rank can influence quality of life dramatically among members of social groups.For example, high-ranking individuals have greater access to resources, including food and mating prerogatives that, in turn, have a positive impact on th

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